http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H0959293-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3c9446a65422eaca792040fe2b817fb5 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7052 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7042 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7076 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-167 |
| filingDate | 1995-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_46d62bf5bfba70b28a6088ea6e51447e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4843ff9373d14777e151982f4dc90dff http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d978f08937ad10974d8ad1eb60526a0c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bda3b5c3db3035cf9ab1d44cf2eb370b |
| publicationDate | 1997-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H0959293-A |
| titleOfInvention | Method for producing 2-position carbon chain-substituted adenosine derivative |
| abstract | (57) [Summary] (Modified) [PROBLEMS] To provide a novel method for producing a 2-position carbon chain-substituted adenosine derivative which is completely different from conventional methods. A method for producing a 2-position carbon chain-substituted adenosine derivative represented by the formula (I) and a novel 2-position carbon chain-substituted adenosine derivative obtained by the following two reaction steps. (In the formula, R 1 represents an alkyl group, a phenyl group, an aralkyl group, etc., and R 2 represents a hydrogen atom or a hydroxyl group-protecting group.) First step: represented by the formula (II) by a lithiating agent and trialkyltin A compound of formula (III) by stannylating the 2-position of the base moiety of the compound. (In the formula, R 3 represents a lower alkyl group, and X represents a halogen atom.) Step 2: After aminating the 6-position of the base moiety of the compound represented by the formula (III), a base is formed by a Stille reaction. A step of introducing a carbon chain at the 2-position and removing a protecting group for the sugar moiety hydroxyl group, if necessary, to obtain a compound represented by the formula (I). |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2007527396-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018047909-A1 |
| priorityDate | 1995-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 72.