| abstract |
(57) [Summary] (Modified) [PROBLEMS] A novel bicyclo compound which has an excellent anxiolytic effect and has very few side effects such as sleep-enhancing effect, muscle-relaxing effect, and sedative effect. A lactam compound and intermediates for producing the same are provided. A bicyclolactam compound represented by the general formula (1), and an anxiolytic drug containing an effective amount of the compound. [In the formula, R is an oxo group or -OR 1 , R 1 is a hydrogen atom or an acyl group, A is a group of the formula (2) or (3) (provided that R 2 has a substituent. Optionally a benzoyl group), Q is a hydrogen atom or a lower alkyl group, 1 is 1 or 2, m is 0 or 1, and n is 0, 1 or 2. However, the case where m and n are 0 at the same time is excluded. ] |