http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H09506892-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D231-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D261-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-64 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D261-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D231-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-41 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-415 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4418 |
| filingDate | 1994-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1997-07-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H09506892-A |
| titleOfInvention | Trisubstituted phenyl derivatives, a process for their preparation and their use as phosphodiesterase (type IV) inhibitors |
| abstract | (57) [Summary] In the compound represented by the general chemical formula (1), and salts, solvates, hydrates, and N-oxides thereof, Y is a halogen atom or an alkyl group in which R 1 is optionally substituted. a group -OR 1 is, X is -O -, - S- or -N R 8 is a hydrogen atom or an alkyl group (R 8) - a is alkyl R 2 is an optionally substituted, alkenyl , A cycloalkyl or cycloalkenyl group, R 3 is hydrogen or a halogen atom, R 9 is a hydrogen atom, or an optionally substituted alkyl, alkenyl, alkoxyalkyl or alkanoyl group, or formyl, carboxamide or thiocarboxy. an -OR 9 group is an amide group, R 4 is a group - (CH 2) a n Ar, Ar of the formula is oxygen, one or more selected from oxygen, sulfur or nitrogen atom A monocyclic or bicyclic aryl group containing a hetero atom optionally, n is zero or an integer 1, 2 or 3, R 5 is optionally oxygen, one or more hetero atoms selected from oxygen, sulfur or nitrogen atom Is a C 3-9 carbocyclic ketone, R 6 is a hydrogen atom or an optionally substituted alkyl group, and R 7 is a hydrogen atom or an optionally substituted alkyl group. The compounds according to the invention are potent and selective phosphodiesterase type IV inhibitors and are useful in the prevention and treatment of diseases such as asthma in the presence of unwanted inflammatory responses or muscle spasms. |
| priorityDate | 1993-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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