http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H09504805-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-073 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-173 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-00 |
| filingDate | 1995-08-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1997-05-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H09504805-A |
| titleOfInvention | Active nucleoside phosphoramidite, process for its production and use thereof |
| abstract | (57) [Summary] The following general formula (I) Where one of R A and R B is R 3 and the other is —P (R 2 ) OR 1 , where R 1 is a substituted arylcarbonyl group and R 2 is R 4 O or it is R 5, R 3 is a hydroxyl protecting group and B has a purine or pyrimidine base.), the active nucleoside derivative formed in situ. Compounds in which R 1 is 2,4-dinitrophenylcarbonyl are particularly preferred. The compounds of general formula (I) are prepared with the corresponding carboxylic acids; these acids are generally readily soluble in acetonitrile (eg about 1.5M for 2,4-dinitrobenzoic acid) and activators at low concentrations. Acts as. The compounds of general formula (I) can be used in conventional coupling reactions (eg solid phase synthesis) to prepare oligonucleotides indistinguishable from those prepared using conventionally known tetrazole activated nucleoside intermediates. |
| priorityDate | 1994-08-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 84.