| abstract |
(57) [Summary] Formula (I): XL-Y, (II): X- (LY) n and (III): XL- (Y) n (wherein X is uracil) A reductase inactivating agent or a prodrug thereof, Y is 5-fluorouracil or a prodrug thereof, L is a linking group covalently bonded to both X and Y, and n is at least 2) , The use of such compounds in medicine, especially in cancer chemotherapy, pharmaceutical compositions containing such compounds, and processes for preparing such compounds are disclosed. |