Predicate |
Object |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-522 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-107 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-63 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-106 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 |
filingDate |
1994-10-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate |
1997-05-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
JP-H09504430-A |
titleOfInvention |
VIBRIOCHOLERAE01 (CVD111) and-NON-01 (CVD112 and CVD112RM) serogroup vaccine strains, methods of making the same, and products thereof |
abstract |
(57) [Summary] The cholera toxin core locus of the cholera toxin locus and the DNA of RS1 sequence are deficient, and further, have a DNA encoding resistance to mercury, and impart a cholera toxin B subunit or immunogenicity. DNA encoding a sufficient portion thereof to have been re-inserted into a chromosome, O1 (CVD111) and non -O1 (CVD112 and CVD112RM) nontoxic Vi Bliocholerae serogroup. The non-toxic V. ch olerae O1 and method of making the non -O1 strain, and cholera vaccine using these strains. |
priorityDate |
1993-10-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |