http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H09503492-A
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C259-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C323-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-165 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C259-06 |
filingDate | 1994-08-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 1997-04-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-H09503492-A |
titleOfInvention | Succinamide derivatives, their preparation and their use as gelatinase and collagenase inhibitors |
abstract | (57) [Summary] A compound represented by the formula (1) (in the formula, R 1 represents (a), R 3 represents a hydrogen or halogen atom, a methyl, trifluoromethyl or methoxy group, and R 2 represents a hydrogen atom. Or a methyl group) and its salts, solvates, hydrates, and prodrugs. The compounds are potent and selective metalloproteinases, long-acting, orally active inhibitors of gelatinases, which in particular inhibit angiogenesis in vivo. Therefore, they can be expected to be used for the prevention or treatment of angiogenesis-dependent diseases such as solid tumors and arthritis diseases. |
priorityDate | 1993-08-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 135.