abstract |
(57) [Summary] In the formula (I), Y is a polypeptide, R 1 is hydrogen, or branched or linear, substituted or unsubstituted C 1-21 alkyl bonded to the N terminus of Y. , Alkylene or alkyne groups, R 2 is the side chain of a naturally occurring amino acid, and X is (a), (b), (c). Such compounds are useful as haptens or immunogens that induce antibodies that catalytically increase the rate of primary amide bond formation or hydrolysis. Methods of using these compounds and antibodies are also described. |