| abstract |
(57) [Summary] (Modified) [PROBLEMS] To provide an antitumor compound. SOLUTION: The pyrimidinylpyrazole derivative represented by the general formula (I) and an antitumor agent containing the compound as an active ingredient. Embedded image [In the formula, R 1 and R 2 are a hydrogen atom, a halogen atom, an alkyl group, an alkoxy group, NH 2 , OH, SH, CN, CONH 2 and the like; R 3 and R 5 represent a hydrogen atom or an alkyl group; R 4 represents a hydrogen atom, an alkyl group, A phenyl group or a benzyl group; R 6 represents a 4- (substituted) phenyl-piperazinyl group, a 4- (substituted) phenyl-4-hydroxypiperidinyl group, a tetrahydroisoquinolyl group, a morpholinyl group, etc.] |