http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H09323937-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5128cfc84a0fb189fceb3cd240c44493 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-00 |
filingDate | 1996-06-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_682d2ca7a10b49c8a67a0510bf67643d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0593bf788b409da5a608a92941a11ad2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f8075217429aafc9718dafc2655c00cf |
publicationDate | 1997-12-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-H09323937-A |
titleOfInvention | Novel platelet production factor |
abstract | (57) [Summary] (Modified) [Solution] A platelet-producing factor having the following properties, a method for producing the same, and a pharmaceutical use thereof. (A) It has megakaryoblastic process formation activity. (B) The activity is not neutralized by the antibody for neutralizing the activity of interleukin-6 and erythropoietin. (C) 10 mM N- (2-hydroxyethyl) piperazine-N′-2-containing 150 mM sodium chloride at pH 7.4. Adsorbs to wheat germ lectin under ethanesulfonic acid (HEPES) buffer conditions. (D) It does not adsorb to the blue dye under the condition of 10 mM phosphate buffer (PBS) having a pH of 7.4 containing 136 mM sodium chloride and 2.7 mM potassium chloride. [Effects] The above substances have megakaryoblastic process formation activity and are capable of producing platelets, and are useful as platelet producing agents that can be used for treatment and prevention of thrombocytopenia. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2002104978-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-4706093-B2 |
priorityDate | 1996-06-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 234.