| abstract |
(57) Abstract: Impurities, especially 4,5-dichloro-2-methyl-4-isothiazolin-3-one Methyl-4-isothiazolin-3-one and 5-chloro- To provide a method for producing a mixture with 2-methyl-4-isothiazolin-3-one, and a stabilized isothiazolone composition or aqueous solution containing such an isothiazolone mixture as an active ingredient. The present invention provides N-methyl-3-mercaptopropionamide or N, N'-dimethyl-3,3 '. A method of carrying out a chlorination reaction and a cyclization reaction using dithiodipropionamide as a starting material, maintaining the temperature in the reaction system at 5 to 20 ° C., and optionally purifying the product mixture by centrifugation after the reaction step. And |