abstract |
(57) Abstract: A therapeutic agent for fungal infections comprising an amino compound (1) or a pharmaceutically acceptable salt of the compound as an active ingredient. Embedded image [Φ is a phenyl group, substituted phenyl group (substituent is a hydroxyl group, 1 selected from the group consisting of a halogen atom, a lower alkoxyl group, a trifluoromethyl group, an amino group, a di-lower alkylamino group, a nitro group and a methylenedioxy group. ~ 5), an imidazolyl group, a pyridyl group, a quinolyl group or an indolyl group. R 1 is H or a lower alkyl group. R 2 is a C6-15 hydrocarbon group which may be substituted with a hydroxyl group. n is 1 or 2. [Effect] It has excellent antifungal activity and high safety, and is useful as a therapeutic agent for deep-seated fungal infections, deep skin fungal infections or superficial fungal infections of humans and animals. |