| abstract |
(57) [Summary] (Modified) [PROBLEMS] To provide a chromone derivative. SOLUTION: The following formula I: (In the formula, ring A may be substituted with lower alkyl, lower alkoxy, halogen, NO 2 , CF 3 , and ring B may be lower alkyl, lower alkoxy, lower alkylthio, halogen, NO 2 , CN, CF 3 The compounds of formula (I) may have the valuable pharmacological properties and are particularly effective as NK1 antagonists and substance P antagonists. The compound is produced by a method known per se. |