http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H09295981-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5b65747ed78f05dd9ebe107b50ce2855 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-048 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D495-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P13-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-10 |
filingDate | 1996-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_117421ed14d4de8f9473ea03fb8e5b31 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_56a52bab93e50470b4d79ce381b2810a |
publicationDate | 1997-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-H09295981-A |
titleOfInvention | Fused hetero 5-membered azepine derivative and pharmaceutical use thereof |
abstract | (57) [Abstract] (Modified) [Problem] Excellent as a preventive or therapeutic drug for diseases associated with vasopressin, such as congestive heart failure, edema, especially cerebral edema, arginine vasopressin hypersecretion syndrome, hypertension, and diuretics. The compound which exerts the said effect is provided. SOLUTION: General formula (I) [In the formula, R 1 , R 2 , R 3 , R 4 , and R 6 represent a hydrogen atom or a lower alkyl group, R 5 represents a hydrogen atom, a lower alkyl group, a phenyl group, or the like, and A 1 represents an oxygen atom. , Sulfur atom or —NR 7 — (R 7 is hydrogen atom or lower alkyl group), A 2 is —CR 8 R 9 — (R 8 , R 9 are hydrogen atom, hydroxyl group or lower alkyl group, etc. One of which is always an atom) etc., A 3 represents an oxygen atom, a sulfur atom, —NR 11 — or a single bond, Z represents a halogen atom, Represents a heterocycle and the like. ] The fused hetero 5-membered ring azepine derivative represented by or its pharmacologically acceptable salt. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0066579-A1 |
priorityDate | 1995-11-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 438.