| abstract |
(57) Abstract: A pharmaceutical composition comprising an antibody effective for ameliorating or avoiding the harmful effects of mediator substances in mammals is provided. SOLUTION: The mediator active composition is biologically active and has an anabolic enzyme, lipoprotein lipase, Suppressing the activities of acetyl coenzyme A carboxylase and fatty acid synthetase, collecting a macrophage cell sample from a mammal from a mammalian macrophage cell, and a part of the macrophage cell to a mammal The procedure of culturing with a stimulator that causes an invasion stimulus, the procedure obtained by inducing the production of the mediator active composition of the macrophages, and the property that the antibody is capable of neutralizing the biological activity. Have. |