| abstract |
(57) Abstract: The present invention provides a novel quinolone derivative useful as a cell adhesion inhibitor. SOLUTION: The formula (I) (In the formula, R 1 represents a substituted or unsubstituted aryl, a substituted or unsubstituted aromatic heterocyclic group, cyano or acetamido, R 2 and R 3 are the same or different, and hydrogen, Represents lower alkyl, halogenated lower alkyl, halogen, hydroxyl, lower alkoxyl, lower alkylthio, nitro, amino, lower alkylamino, dilower alkylamino, lower alkanoylamino, or lower alkoxycarbonyl, and R 4 and R 5 are the same or Differently representing hydrogen or lower alkyl, n and m are 0, 1, Represents an integer of 2. ) A quinolone derivative represented by or a pharmacologically acceptable salt thereof. |