http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H09278658-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ba1802c543086d0b26d1da2a8add0d0c |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04 |
| filingDate | 1996-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ea12327c1565883d3f8d7b2caf967347 |
| publicationDate | 1997-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H09278658-A |
| titleOfInvention | New IFN Inducer |
| abstract | (57) Abstract: An object of the present invention is to find a novel IFN inducer. According to the present invention, it has been found that single-stranded DNA derived from M13 phage is exceptionally effective as an IFN inducer. Within 4 hours after administration of single-stranded DNA derived from M13 phage (M13 DNA), serum interferon (IFN, predominantly β-type) titers were about 700 I from undetectable levels. IFN was detected over as long as 12 hours after further administration, increasing to as much as U / ml. In addition, when M13 DNA was added to the spleen medium, a large amount of I such as 1050 IU / ml was detected at an undetectable level. Induction of NF was detected in vitro (see Figure 1). Therefore, M13 DNA proved to be a strong IFN inducer. |
| priorityDate | 1996-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 60.