http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H09268172-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f7c7159366be37ecf8a4c595cfa235a8 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D521-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C317-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C311-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-165 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C323-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C279-22 |
| filingDate | 1996-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7c2765866b47ae6e1d4e511c2968947a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7b94f15060b9feef86840bcd2308c76b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_630e3715a08aa4e1be62daf2baa06848 |
| publicationDate | 1997-10-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H09268172-A |
| titleOfInvention | Novel substituted guanidine derivatives and their preparation |
| abstract | (57) Abstract: Diseases caused by enhancement of sodium / proton (Na + / H +) exchange transport system, such as hypertension, arrhythmia, Useful as a therapeutic or prophylactic drug for angina, cardiac hypertrophy, diabetes, organ damage caused by ischemia or ischemia-reperfusion, cerebral ischemia damage, diseases caused by cell hyperproliferation, diseases caused by endothelial cell damage, etc. A novel substituted guanidine derivative or a salt thereof and a method for producing the same are provided. SOLUTION: General formula (1) [In the formula, Z represents CR 6 R 7 , C = O or C = R 8 R 9 , and R 1 , R 2 , R 3 and R 4 are each independently a hydrogen atom, an alkyl group or a substituted alkyl group, It represents a halogen atom or the like, and R 5 represents a hydrogen atom or the like. Or a pharmaceutically acceptable acid addition salt thereof. |
| priorityDate | 1996-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 161.