abstract |
(57) Abstract: A method for obtaining an optically active substance of a fluorine-containing hydroxy compound from an easily available raw material in high yield is provided. A fluorine-containing keto compound CH n F 3-n -CO- R a, by hydrogenation reaction in the presence of a nickel catalyst supported an optically active compound, to obtain an optically active, fluorine-containing hydroxy compound CH n F 3-n -C * H (OH) -R. n is 0 2, R represents an alkoxycarbonylalkyl group, etc., * represents an optically active carbon. |