abstract |
(57) Abstract: Glycoprotein (TCF-II) having antitumor activity and other physiological activities, a preparation containing the glycoprotein as an active ingredient, and a DNA encoding the same. SOLUTION: A molecular weight of 78,000 ± 2,000 or 74,000 obtained by subjecting a supernatant of human-derived fibroblasts to chromatograph processing Glycoprotein with an isoelectric point of ± 2,000 and an isoelectric point of 7.4 to 8.6, and a DNA encoding the glycoprotein. A stable preparation obtained by adding a protein, a nonionic surfactant or a saccharide to this glycoprotein. Used as an antitumor agent and other medicines. |