| abstract |
(57) Abstract: To provide a monoclonal antibody and a reagent for measuring human PIVKA-II in a sample. SOLUTION: The formula: A hybridoma is prepared by fusing a lymphocyte obtained by immunizing a mammal with an immunogen comprising the peptide represented by the above and a myeloma cell of the mammal, and then an anti-human PIVKA-II monoclonal antibody is obtained from this hybridoma. A measurement reagent is produced using this antibody, and human PIVKA-II contained in the sample is immunoassayed. |