http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H09249666-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5929f2d6f4dba84be8dd3a8ba633db12 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-435 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P13-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-495 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P15-00 |
filingDate | 1996-09-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1d0996f5ed72d18ebd2f31194d9a6842 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2e03853fb2f7dab8c03691955eaf37b1 |
publicationDate | 1997-09-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-H09249666-A |
titleOfInvention | Process for producing tricyclic compound and intermediate thereof |
abstract | (57) [Summary] (Modified) [PROBLEMS] To provide a convenient and efficient industrially advantageous production method of a tricyclic compound useful as a new therapeutic agent for the circulatory system and a useful synthetic intermediate. . A compound represented by the formula (I) or a salt thereof, a compound represented by the formula (I) (wherein R 3 is a halogenated methyl group) or a salt thereof, and a compound represented by NH 2 —R 5 A compound of formula (IV) A method for producing the compound represented by or a salt thereof. [Wherein R is a halogen atom, a (substituted) lower alkoxy group, a (substituted) hydrocarbon group, etc .; R 1 is hydrogen, a (substituted) hydrocarbon group, etc .; R 2 is a protected carboxyl group; R 3 is ( (Substituted) methyl group; R 5 represents (substituted) hydrocarbon group, (protected) hydroxyl group; n is an integer of 0 to 3] [Effect] The compound of formula (IV) is excellent in platelet-derived proliferation. Factor inhibitory action, antihypertensive action, mesangial cell proliferation inhibitory action, It has a renal disease improving action and a lipid lowering action. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9309238-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9908876-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10913737-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10919888-B2 |
priorityDate | 1996-01-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 181.