http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H09249602-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1374dd16777534b65ad4422333245af8 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-52 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-297 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C35-27 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F7-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B53-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C201-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C205-41 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J31-22 |
| filingDate | 1996-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5a3e031c2c78c88ee6aed81c1b9b7b78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7995e5ab03618992c6a209e5213bcfe0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_acd55f0399bf4c68ee3221b17e90bdf5 |
| publicationDate | 1997-09-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H09249602-A |
| titleOfInvention | Process for producing indene compound and its synthetic intermediate |
| abstract | (57) Abstract: To provide a simple and highly stereoselective method for producing a synthetic intermediate for a CD ring portion, which is used in the synthesis of 1α, 24-dihydroxyvitamin D 3 . SOLUTION: 4- (4-Substituted inden-1-yl)- Pentanals or 4- (4-substituted indene-1- Yl) -2-pentenal and 2-nitropropane are subjected to an asymmetric nitroaldol reaction in the presence of a dinuclear catalyst consisting of a rare earth-binaphthol derivative-potassium to give a nitroaldol compound, and further in the presence of a radical initiator. By the reaction of tributyltin hydride with the following formula (IV) [In the formula, R represents a hydrogen atom, an acyl group having 2 to 8 carbon atoms, or a tri (hydrocarbon group having 1 to 6 carbon atoms) -substituted silyl group, and A and B are both hydrogen atoms, or A And B together represent a carbon-carbon bond, and the * mark indicates that the isomer derived from the asymmetric carbon is biased to one isomer. ] The manufacturing method of the indene compound represented by these, and the said nitro aldol compound. |
| priorityDate | 1996-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 68.