| abstract |
(57) Abstract: A novel phenol derivative useful as an excellent drug is provided. SOLUTION: General formula [I] (Wherein OR 0 is a hydroxyl group which may be protected, R 1 is a hydrogen atom or a lower alkyl group, R 2 is a hydrogen atom or a lower alkyl group which may have a substituent, and R 3 has a substituent. Optionally a phenyl group, X is O, S or NR 8 , R 8 is a hydrogen atom, a lower alkyl group, an aryl group, Hydroxyl group or lower alkoxy group, R 4 , R 5 , R 6 and R 7 (1) R 4 is a hydrogen atom, R 5 , R 6 and R 7 are a hydrogen atom, an alkoxy group or a lower alkylthio group, or (2) R 4 is an alkoxy group or a lower alkylthio group, R 5 and R 7 represent a hydrogen atom, an alkoxy group or a lower alkylthio group, and R 6 represents a hydrogen atom. ) Phenol derivative (provided that 2- (3- Phenylureido) -4-methoxyphenol and 2- {3- (3,4-dichlorophenyl) ureido} -4- Excludes methoxyphenol. ) Or a pharmacologically acceptable salt thereof. |