| abstract |
(57) [Abstract] [Purpose] [Constitution] General formula (1) (In the formula, R 1 represents an aromatic hydrocarbon group such as a naphthyl group which may have a substituent; A represents a sulfone group or a sulfonamide which may have a substituent on the nitrogen atom. Group, an amide group; R 2 represents a hydrocarbon group having 1 to 10 carbon atoms; G represents an amino group which may have a substituent, or a cyclic amine such as piperazine or homopiperazine. R 3 represents a hydrocarbon group having 1 to 18 carbon atoms which may have a substituent and in which a hetero atom may be present at any position.) Or A pharmaceutically acceptable salt thereof. [Effect] The compound of the present invention has a proliferation inhibitory action on vascular smooth muscle cells and an inhibitory action on cyclic contraction, It is useful as a therapeutic agent for angina pectoris, which has an effect of preventing restenosis after TCA. |