abstract |
(57) 【Abstract】 PROBLEM TO BE SOLVED: To have a high inhibitory activity against human pancreatic α-amylase, to suppress increase in blood glucose level in humans, to control insulin secretion, to be able to eat food by maintaining satiety, and to have hyperglycemia. , To provide an amylase inhibitor effective for prevention and treatment of diabetes, hyperlipidemia, arteriosclerosis, obesity and the like. A novel amylase inhibitor of the present invention, which is a protein consisting of two subunits, which is a conjugate of 122 amino acids, which gives a single band at the position of mobility 0.26 by polyacrylamide gel electrophoresis. The above-mentioned object can be achieved by a substance, an amylase inhibitor containing the same as an active ingredient, a blood sugar level increase inhibitor, an insulin secretion regulator, an appetite suppressant and the like. |