| abstract |
(57) Abstract: The present invention provides a pharmaceutical composition comprising as an active ingredient a propiophenone derivative exhibiting excellent urinary glucose increasing action and hypoglycemic action based on inhibition of glucose reabsorption in the kidney. Is. SOLUTION: General formula [I] [Wherein, X is an oxygen atom, a sulfur atom or a methylene group, OY is an optionally protected hydroxyl group, and Z is β. -D-glucopyranosyl group, 4-O- (α-D-glucopyranosyl) -β-D-glucopyranosyl group or a group in which one or more hydroxyl groups thereof are acylated, and a dotted line indicates the presence or absence of a double bond. Exists. ] The pharmaceutical composition which uses the propiophenone derivative shown by these, or its pharmacologically acceptable salt as an active ingredient. |