| abstract |
(57) Abstract: An anti-hair graying agent containing a chromone derivative represented by the following general formula (1) or a salt thereof as an active ingredient. Embedded image [R 1 is H, an alkyl group, COOH, COOR 9 (R 9 is a C1-C15 linear or branched alkyl or alkenyl group or a group of the formula (2) (R 7 and R 8 are H, an alkyl group, or R 7 and R 8 are taken together. alkylene or -CH 2 CH 2 OCH 2 CH 2 - and the form), R 2 Is H, an acyl group or COOH, R 3 is H, OH, a lower alkoxyl group, a carboxymethyloxy group or a lower alkoxycarbonylmethyloxy group, and R 4 is H, O. H, OR 6 (R 6 has the same meaning as above), lower acyloxy group, carboxymethyloxy group, lower alkoxycarbonylmethyloxy group or aralkyloxy group, and R 5 is H, OH, alkyl group or lower alkoxy Group] [Effect] It exerts a remarkable effect of preventing and improving gray hair. |