| abstract |
(57) Abstract: A novel 17α-cyanomethyl estra, whose production and biological effects have never been described. Providing 4,9-diene derivatives. SOLUTION: A general formula I: [Wherein, R 1 represents an alkyl group having 1 to 2 carbon atoms, R 2 represents an alkyl group having 1 to 10 carbon atoms, an acyl group having 1 to 10 carbon atoms, or tri R 3 represents an oxygen atom or a R—O—N— group, wherein R represents a hydrogen atom, 1 Represents an acyl group having 10 to 10 carbon atoms, an alkyl group having 1 to 10 carbon atoms, a sulfamoyl group, an alkyl- or trialkylsilyl group], and is represented by the formula 17α-cyanomethyl estra-4,9-diene Derivative. |