| abstract |
(57) [Summary] [Structure] The following general formula (I): [In the formula, R 1 is an A-CO-CH = CH- group (A is a phenyl group, etc.) or an amino group represented by NHR 2 (R 2 is a hydrogen atom, a lower alkyl group, a phenyl group, etc.); Atom or an imino group represented by NR 3 (R 3 is a hydrogen atom, a lower alkyl group, etc.); Y is an oxygen atom or a sulfur atom], and an N-benzoylproline ester derivative is represented. [Effect] The compound (I) of the present invention is CCK-A, CCK- Since it has a B and gastrin receptor antagonistic action and exhibits a strong antibacterial action against Helicobacter pylori, it is useful as a preventive and therapeutic drug for digestive system diseases. |