Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_402cc9668a7d8f1bb8bce45e595d073b |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-06 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-18 |
filingDate |
1996-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b8267b29da90e2c56c2bb0d6c8163946 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e2ecd9dfa6d225ce92bdd423ba8f485a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c8423d52f4cfa80f0cbb0e7d5ced7f21 |
publicationDate |
1997-07-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
JP-H09173094-A |
titleOfInvention |
Novel glycopeptide and method for producing the same |
abstract |
(57) [Summary] [Object] To provide a novel complex glycopeptide in which a sugar chain is added to peptide T which is an anti-AIDS virus (anti-HIV) active peptide. [Structure] 1) A novel complex glycopeptide represented by the following formula (Formula 1). Embedded image (In the formula, R 1 is Ala-Ser-Thr-Thr-Th. r, Thr-Thr or D-Ala-Ser-Th shows a peptide residue consisting of r-Thr-Thr, X Is a protecting group for H or N-terminal α-amino group, and Y is O H or NH 2 . R 2 represents a complex type sugar chain, a high mannose type sugar chain or a mixed type sugar chain. 2) A method for producing a novel glycoconjugate represented by (Chemical Formula 1) by transferring a sugar chain of a glycoconjugate to a synthetic peptide having an N-acetylglucosamine (GlcNAc) residue in the presence of endoglycosidase. [Effect] By providing a sugar chain, a more effective bioactive glycopeptide having improved stability and pharmacological action is provided. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019036417-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014066889-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11779592-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2014156409-A |
priorityDate |
1995-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |