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publicationDate 1997-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-H09169645-A
titleOfInvention Ibudilast-containing sustained-release preparation and method for producing the same
abstract (57) [Abstract] [Problem] Balance of solubility so that sufficient initial effect and sustained effect can be stably obtained, which can be produced by a normal method that is easy to put into practical use without using special machinery and equipment. To provide a well-controlled, sustained release formulation containing ibudilast. SOLUTION: Ibudilast is formed into a single granular preparation by forming an inner core granular material containing a specific binder and a carrier fine powder in a solid solution matrix and a coating layer of a drug release controlling substance on the surface thereof.
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