| abstract |
(57) Abstract: [PROBLEMS] To provide a skin external preparation having a synergistically enhanced activity of eliminating active oxygen species and capable of preventing skin aging and damage caused by oxidative stress inside and outside a living body. SOLUTION: One or more kinds selected from adenosine and its derivative having a hydroxy radical scavenging activity, and Hamamelitannin, Hamamelis, oak, fart, Marronnier, Waremoko, button extract, thioredoxin, thioredoxin reductase and their complex, It is combined with an external preparation base in combination with a reactive oxygen species scavenger selected from a placenta extract. Examples of the adenosine derivative include adenosine monophosphate, adenosine diphosphate, adenosine triphosphate, and cyclic adenosine monophosphate. |