| abstract |
(57) Abstract: Provided is an industrially effective production method for synthesizing nitrogen-containing heteroaromatic amides having a carbamoyl group in a high yield. A nitrogen-containing heteroaromatic ester compound represented by the following general formula (A) is reacted with an amine represented by the following general formula (B) in the presence of a Lewis acid. A method for producing a nitrogen-containing heteroaromatic amide represented by (C). (In the formula, X represents an atomic group capable of forming a 5- or 6-membered heteroaromatic ring, R 1 represents an alkyl group, and R 2 and R 3 are each a hydrogen atom, an alkyl group, an aryl group, or a hetero group. It represents a ring group and may be bonded to each other to form a ring.) |