| abstract |
(57) [Abstract] [Problem] Estriol has high transdermal absorbability, and (EN) Provided is a patch which has low skin irritation, is safe to living organisms, and has good patchability without adhesive residue. A patch comprising a support and a pressure-sensitive adhesive layer comprising a pressure-sensitive adhesive and other components laminated on one surface thereof, wherein the pressure-sensitive adhesive has a (meth) acryl having an alkyl group having 1 to 18 carbon atoms. It is an acrylic pressure-sensitive adhesive copolymerized with 45 to 97% by weight of acid alkyl ester and 3 to 55% by weight of vinylpyrrolidone, and the content of the other component and its content in the pressure-sensitive adhesive layer is estriol 0.1 to 0.1. 20% by weight, isopropyl myristate 10 to 40% by weight, at least one selected from the group consisting of lauric acid diethanolamide, lactic acid and polyoxyethylene lauryl ether. A patch containing 5 to 10% by weight and 1 to 20% by weight of silicic acid anhydride. |