http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H09135689-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_02ff914937eb6ceaee5ca69cc56cbfa7 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1205 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P19-04 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-865 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04 |
| filingDate | 1995-11-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2801371ff4525b9a00fe6410bc7e53e1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5cf275e9d93880ef75f2d2d35158b671 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6b47a3e9edeba1cc62900af706b9e66c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fe1dde0d3b6e26ae01ef718d0fb98d20 |
| publicationDate | 1997-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H09135689-A |
| titleOfInvention | Yeast mannose-1-phosphate transferase gene and method for producing mannose-1-phosphate-containing acidic sugar chain and phosphate-containing acidic sugar chain using the same |
| abstract | (57) Abstract: Yeast (Saccharomyces cerevisiae) mannose-1-phosphate transferase gene, yeast cells transformed with plasmid DNA into which the gene has been introduced are cultured in a medium, A method for producing a mannose-1-phosphate-containing acidic sugar chain, which comprises obtaining a mannose-1-phosphate transferase and allowing it to act on a neutral core sugar chain in vivo or in vitro, and the mannose- 1- A method for producing a phosphoric acid-containing acidic sugar chain, which comprises removing a mannose portion by acid-treating a phosphoric acid-containing acidic sugar chain. [Effects] According to the present invention, an acidic sugar chain obtained by adding mannose-1-phosphate to the same neutral core sugar chain as that of high-mannose produced by mammalian cells such as human is produced by a genetic engineering method using yeast. A large amount and high purity can be produced. Furthermore, to produce a large amount of a useful acidic sugar chain identical to the human-derived phosphate-containing core sugar chain, which can function as a marker for glycoprotein transport to lysosomes in mammalian cells such as humans, in high purity. You can |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-4742191-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2002369692-A |
| priorityDate | 1995-11-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 405.