| abstract |
(57) [Summary] (With correction) [Solution] The following formula (I) [In the formula, A is alkylene which may be substituted, and B is-. CO 2 H, —NHSO 2 CF 3, etc., R 1 , R 2 , R 3 , R 4 and R 5 are hydrogen, hydroxyl, halogen, cyano, etc., and m is 0 or 1, and the substituted quinoline-2-carboxylic acid amide represented by Intermediates in their use and in the preparation of the above compounds. The above compounds are useful as inhibitors of prolyl 4-hydroxylase and agents for the treatment of fibrosis. |