http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H09121858-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4642bec38a16d849ed08e47d76705437 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0ae6565187817f736442dd0a77a31c7b |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-6472 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-06 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-48 |
| filingDate | 1995-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0609e28dacdad8266238bfd50b0c65f6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_20254d3b2cfa52477a104c515fd658ec |
| publicationDate | 1997-05-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H09121858-A |
| titleOfInvention | Immune tolerance inducer |
| abstract | (57) Abstract: A placenta of a mammal is crushed to obtain a homogenate, the homogenate is centrifuged, and the resulting supernatant is subjected to affinity chromatography (I), ion exchange chromatography, gel chromatography. And an SH-dependent protease having the following physicochemical properties, which is obtained by sequentially applying affinity chromatography (II). Action: L-prolyl-L-phenylalanyl-L-arginine 4-methyl- Decomposes coumaryl-7-amide to produce L-prolyl-L-phenylalanyl- Produces L-arginine and 7-amino-4-methyl-coumarin; Optimum pH range: 5.6 ~ 6.5; Optimal temperature range of action: 36.5 ~ 37.5 ℃; stability: -80 ℃, keep the activity for 30 days or more, 100 Completely inactivated by heat treatment at 3 ° C for 3 minutes; molecular weight: 30 kDa. The present invention provides a novel SH-dependent protease and an immunological tolerance inducer containing the protease as an active ingredient. |
| priorityDate | 1995-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 57.