http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H09119916-A

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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J20-281
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filingDate 1995-10-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e15670d540dc80aebc2c07fe34bc2704
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publicationDate 1997-05-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-H09119916-A
titleOfInvention Quantitative analysis method for trace compounds
abstract (57) Abstract: The present invention is a method for quantitatively analyzing a target compound having a very small content in a biological sample using a high performance liquid chromatography / mass spectrometer system (LC-MS / MS). Regarding SOLUTION: (1) The high performance liquid chromatography column has an inner diameter of 1.0 to 4.6 mm, a length of 1 to 25 cm, and a reverse phase packing material having a particle size of 3 to 10 μm. (2) Mass spectrometer is 0.1 pg / ml or more and 10 pg / ml S / N ratio is 3 or more when measured by injecting a quantitative target compound of less than 1 and setting the optimized product ion to a capture width of 1 mass unit or more and 2 mass units or less. (3) Sample The content of the target compound in the assay is 1 μg If it is less than / ml, the lower limit of quantification is 0.1 pg or more and 10 p A quantitative analysis method using a high performance liquid chromatography / mass spectrometer system (LC-MS / MS), characterized in that a relative standard deviation of 20% or less per g is realized with good reproducibility.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03043053-A1
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http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2005099015-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2017151111-A
priorityDate 1995-10-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 30.