http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H09119916-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9f1ea224157140ca3b178d91cf2a0f6f |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J20-281 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-72 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-88 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N27-62 |
filingDate | 1995-10-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e15670d540dc80aebc2c07fe34bc2704 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5a990cc36a134e5f8531a1ac6f30cff9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_50e4e23121802e560851c2db288a4201 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_44e9d0f9341b24809abf46c945f0f67d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6e6d399ee15eeb418d2b4192f09b7fd5 |
publicationDate | 1997-05-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-H09119916-A |
titleOfInvention | Quantitative analysis method for trace compounds |
abstract | (57) Abstract: The present invention is a method for quantitatively analyzing a target compound having a very small content in a biological sample using a high performance liquid chromatography / mass spectrometer system (LC-MS / MS). Regarding SOLUTION: (1) The high performance liquid chromatography column has an inner diameter of 1.0 to 4.6 mm, a length of 1 to 25 cm, and a reverse phase packing material having a particle size of 3 to 10 μm. (2) Mass spectrometer is 0.1 pg / ml or more and 10 pg / ml S / N ratio is 3 or more when measured by injecting a quantitative target compound of less than 1 and setting the optimized product ion to a capture width of 1 mass unit or more and 2 mass units or less. (3) Sample The content of the target compound in the assay is 1 μg If it is less than / ml, the lower limit of quantification is 0.1 pg or more and 10 p A quantitative analysis method using a high performance liquid chromatography / mass spectrometer system (LC-MS / MS), characterized in that a relative standard deviation of 20% or less per g is realized with good reproducibility. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03043053-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109900828-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2005099015-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2017151111-A |
priorityDate | 1995-10-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 30.