| abstract |
(57) [Summary] [Object] To provide a compound having an excellent inhibitory effect on platelet aggregation and exhibiting good oral activity. [Constitution] Formula [Formula 1] [Wherein R 1 is the formula: (In the formula, R 11 and R 12 each represent a hydrogen atom, an alkyl group, an alkoxycarbonyl group, a cycloalkyl group, a phenyl group, a substituted phenyl group, an aralkyl group or a substituted aralkyl group.), A group represented by the formula: Chemical 3] (In the formula, R 21 and R 22 each represent a hydrogen atom or an alkyl group, m and n each represent an integer of 1 to 3, A is a methylene group, a carbonyl group, an ethylenedioxymethylene group, an oxygen atom, a sulfur atom, a sulfinyl group, a sulfonyl group, or a compound represented by the formula: Represents a group represented by. ) Or an imidazolin-2-yl group, R 2 represents an alkyl group, a cycloalkyl group or a phenyl group, R 3 represents a hydrogen atom or an alkyl group, and R 4 represents an alkyl group. ] The thiazoline derivative and its salt represented by these. |