| abstract |
(57) [Summary] [Object] To provide a method for producing α1 protease inhibitor conveniently in a large scale and a method for preparing an α1 protease inhibitor preparation which is safer against the risk of infection by a contaminating virus. [Constitution] The solution containing α1 protease inhibitor is developed on a cation exchange resin to adsorb the contaminated impure protein, The high-purity α1 protease inhibitor is separated into non-adsorbed fractions, which are collected. Sucrose and citrate ions are allowed to coexist during the heat inactivation treatment of infectious contaminant viruses. |