| abstract |
(57) [Summary] [Objective] To provide a non-toxic solubilization method for hydrophobic substances. [Structure] A hydrophobic substance is dissolved using lysophosphatidylethanolamine, and then an organic solvent is removed to obtain a film. The film has a p of between about 6.0 and about 8.0. A method for solubilizing a hydrophobic substance, which comprises the steps of hydrating with H in an aqueous medium, and further cooling the lipid dispersed in the aqueous medium to a temperature of about 0 ° C or lower. [Effect] It is possible to solubilize a hydrophobic substance, particularly a biologically active substance, in a non-toxic manner, and to provide an effective drug administration method. |