abstract |
(57) [Summary] (Modified) [Structure] A method for producing a salicylic acid derivative represented by the general formula 1 by reacting an aminosalicylic acid derivative with a halogenoformate in the presence of a trialkylamine. (X 1 and X 2 are a hydrogen atom, an alkyl group, an alkoxy group, The aralkyl group, the aryl group or the halogen atom is replaced by Y 1 And Y 2 are oxygen or sulfur atoms, R 1 is a hydrogen atom, an alkyl group, an aralkyl group or an aryl group, and R 2 is an alkyl group, an alkenyl group, an aralkyl group or an aryl group. It is possible to provide a method for producing a substituted salicylic acid derivative in high yield. |