| abstract |
(57) [Summary] [Purpose] High purity (> 99%), very high specific activity (> 135 mCi / mmol), and moderate stability (> 3). Labeled glycerol nitrates with 0 days). The present invention relates to a method for preparing [1,3- 14 C 2 ] -glycerol-dinitrates, which liberates carbon dioxide from radioactive barium carbonate; obtains the carbon dioxide in an inert organic solvent. Reducing; reacting the obtained 14 C-formaldehyde compound with nitromethane; reducing the obtained [1,3- 14 C 2 ] -dihydroxyacetone compound in an inert organic solvent; thus obtained [ The 1,3- 14 C 2 ] -glycerol compound was nitrated with a mixture of nitric acid and sulfuric acid, and the resulting [1,3- 14 C 2 ] -glycerol-1,2-dinitrate and [1,3 - 14 C 2] - glycerol-1,3 -Comprising separating the mixture of dinitrates into each. |