abstract |
(57) Abstract: A novel physical form of a dihydro-2,3-benzodiazepine derivative useful as an AMPA antagonist in the treatment of nervous system disorders, a method for producing the same, a pharmaceutical composition containing the same, and use thereof. Provide a way. The problem is that the distance d is 12.78 and 9.4. 8, 8.99, 8.64, 8.23, 6.39, 6.27, (R) -7-Acetyl-5- (4-aminophenyl) -8,9-dihydro-8-methyl-7H having an X-ray powder diffraction pattern of 5.73, 4.01 and 3.96Å. -1, The solution is to provide 3-dioxolo [4,5-h] [2,3] benzodiazepine as Form (IV). |