| abstract |
(57) [Summary] (Modified) [Objective] To provide an antitumor agent containing a 1,8-naphthyridine derivative as an active ingredient. [Structure] An antitumor agent comprising a 1,8-naphthyridine compound represented by the general formula (I), an ester thereof, or a salt thereof as an active ingredient. (In the formula, R represents a hydrogen atom, a lower alkyl group or a lower alkoxy group, Z represents a hydrogen atom, a lower alkyl group or a group convertible into a hydrogen atom in vivo, and n represents 0 or 1, respectively.) [Effect] It has excellent antitumor activity. |