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(57) [Abstract] [Purpose] 1,4-disubstituted-1,4-diaminobutane- Provided is an efficient and economical method for producing a 2-ol derivative, particularly a threo configurational isomer useful as an intermediate for producing an HIV protease inhibitor. [Structure] General formula (1) (wherein R 1 is an alkyl group, Represents an aralkyl group or an aryl group. R 2 and R 3 independently represent a hydrogen atom or an amino group-protecting group. However, Except when R 2 and R 3 are simultaneously hydrogen atoms. ) A general formula (2) for stereospecifically reducing a cis-type epoxy derivative or its enantiomer represented by (In the formula, R 1 , R 2 and R 3 are the same as defined above.) A method for producing a 1,4-diaminobutan-2-ol derivative or an enantiomer thereof. Embedded image Embedded image |