| abstract |
(57) [Summary] [Structure] A heterocyclic derivative represented by the following general formula (I) or a salt thereof: (Each symbol in the above formula has the following meaning. A ring group: imidazolyl group, tetrazolyl group, R 1: a hydrogen atom, a halogen atom, a lower alkyl group, a hydroxy lower alkyl group, a lower alkoxy group, a trifluoromethyl group, a nitro group, a carboxyl group, lower alkoxycarbonyl group, the formula -CH 2 -NHCONH-COOR A group represented by 5 or a group represented by the formula -CH = N-OH, R 2, R 3: same or different and each represents a hydrogen atom or a halogen atom, R 4: a hydrogen atom or a hydroxyl group, R 5: a hydrogen atom or a lower alkyl group, X: an oxygen atom, a sulfur atom or the formula -NH- A group represented by Y: nitrogen atom or And n: 0 or 1) [Effect] It has a blood glucose lowering action based on the insulin sensitivity enhancing action, and is useful as an antidiabetic agent and the like. |