| abstract |
(57) [Summary]nProvided an aqueous solution consisting of a polysaccharide swelling agent, a physiologically compatible buffer, a single hexose, dissolved calcium, sodium, magnesium chloride, dissolved sodium organic salts. . This solution is an effective substitute for blood, and as indicated by the excellent anatomical integrity of cryopreserved organs and tissues of the subject animals perfused with this solution, it is of mammalian origin. It can be used to preserve the biological integrity of the organ of a donor organism. The solution can be used to maintain a partially or substantially completely exsanguinated target animal at normal temperatures and temperatures substantially below those normally maintained by mammals, and Such a partially or completely exsanguinated subject animal can be used to keep alive without transfusing blood to the subject animal. |