| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2123-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-6561
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-106
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-0482 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F15-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-44
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-675
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-6561
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F13-00 |
| filingDate |
1993-05-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate |
1996-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-H08509976-A |
| titleOfInvention |
Bicyclopolyaza macrocyclophosphonic acids for use as contrast agents, complexes and composites thereof and processes for their preparation |
| abstract |
(57) [Summary]nDisclosed are bicyclopolyaza macrocyclophosphonic acid compounds capable of forming an inactive complex with Gd, Mn or Fe ions. In vivo biolocalization can be altered by varying the complex over a wide range. Such a complex can be covalently bound to an antibody, antibody fragment or other biologically active molecule to form a complex. Complexes and conjugates are useful as contrast agents for diagnostic purposes. Also disclosed are methods of making the ligands, complexes and conjugates. |
| priorityDate |
1993-05-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |